VCFs can lead to severe back pain, loss of mobility, spinal deformities, and even neural compromise with neurologic deficits 2, 3. Vertebral compression fractures (VCFs) account for one-fourth of all osteoporotic-related fractures 1. By 2025, 3 million osteoporotic fractures and $25 billion in related health care costs will occur in the USA 1. Any sudden force of axial compression, distraction, and/or rotation on brittle bone could lead to osteoporotic fractures. Osteoporosis in the elderly population remains a major public health challenge. HVC VP might be a good alternative to LVC BKP in the treatment of osteoporotic VCFs in high to mid-thoracic spine. The outcomes of LVC BKP were not superior to that of HVC VP. The LVC BKP group corrected more middle vertebral body height and local kyphosis angle than the HVC VP group. Compared with preoperative data, the VAS was improved after surgery in both groups. Leakage rate of cement was also fewer in the HVC VP group (26/72 vs. The operation time (minutes) of the HVC VP group was significantly less than that of the LVC BKP group (33.34 vs. More volume (ml) of cement injection was seen in the LVC BKP group (4.40 vs. Radiographic data were collected preoperatively, postoperatively, and at final follow-up. Clinical outcomes including demographic data and visual analogue scale (VAS) were compared. All patients were divided into the HVC VP group (n = 72) and the LVC BKP group (n = 42). A total of 114 patients with painful collapsed single-level vertebrae at high to mid-thoracic level who had undergone HVC VP or LVC BKP at a single tertiary medical center was reviewed retrospectively. The purpose of this study was to identify the different outcomes between HVC VP and LVC BKP used to repair high (T4–6) and mid (T7–9)-thoracic VCFs. Whilst the majority of the literature suggests that balloon kyphoplasty (BKP) can relieve pain associated with vertebral compression fractures (VCFs), evidence of high-viscosity cement (HVC) vertebroplasty (VP) or low viscosity cement (LVC) BKP for the treatment of VCFs at the levels of high and mid-thoracic vertebrae remains limited.
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